GNF 2

目录号: A11439

Bcr-Abl 抑制剂

GNF 2

GNF 2 Chemical Structure

CAS NO. 778270-11-4

GNF 2是一种Bcr-abl抑制剂,在表达Bcr-abl的细胞中抑制增殖并诱导凋亡。

库存: 现货

规格 价格 数量
10 mg
¥ 1,200.00
25 mg
¥ 2,500.00
50 mg
¥ 4,500.00
10mM * 1mL in DMSO
¥ 1,040.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

GNF 2是一种Bcr-abl抑制剂,在表达Bcr-abl的细胞中抑制增殖并诱导凋亡。
靶点信息
Bcr-Abl (SUP-B15 cell line) Bcr-Abl (K562 cell line)
268 nM273 nM
In vitro DMSO 67 mg/mL (178.99 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.72 mL 133.58 mL 267.17 mL
0.5 mM 5.34 mL 26.72 mL 53.43 mL
1 mM 2.67 mL 13.36 mL 26.72 mL
5 mM 0.53 mL 2.67 mL 5.34 mL

*The above data is based on the productmolecular weight 374.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11439
作用机制 Inhibitor (抑制剂)
M. Wt 374.3
Formula C18H13F3N4O2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 778270-11-4
Synonyms GNF2,GNF-2
SMILES C1=CC(=CC(=C1)C(=O)N)C2=CC(=NC=N2)NC3=CC=C(C=C3)OC(F)(F)F

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