GNF 5837

Name: GNF 5837
SKU: A13730
Price: 280 CNY
Rating: 5 (3 reviews)

目录号: A13730

TRK 抑制剂

3 篇发表文献

GNF-5837 是一种有效的、选择性的、可口服的全泛TRK抑制剂，它在来源于同时表达TRKA和NGF的RIE细胞的小鼠异种移植模型中抑制了肿瘤生长。

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Grouped product items
规格	价格	库存
5mg	¥280.00	现货
10mg	¥490.00	现货
25mg	¥840.00	现货
50mg	¥1,330.00	现货
100mg	¥2,240.00	现货
200mg	¥2,940.00	现货
500mg	¥4,795.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
更大包装	更多折扣

大包装询价

Notify me when the price drops

全国免运费, 顺丰次日达

重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用GNF 5837发表的3篇文献

Tanimizu N, .et al. , Development, 2018, Apr 25;145(9). pii: dev159095 PMID: 29615468

Shargh VH, .et al. , Nanomedicine (Lond), 2017, May;12(9):977-989 PMID: 28440712

Shargh VH, .et al. , Int J Pharm, 2016, Dec 30;515(1-2):527-534 PMID: 27793712

生物活性

Discription

GNF-5837 is a potent, selective, and orally bioavailable pan-TRK inhibitor that inhibited tumor growth in a mouse xenograft model derived from RIE cells expressing both TRKA and NGF.

Targets

Target	Value

产品信息

目录号	A13730
分子式	C28H21F4N5O2
分子量	535.49
CAS号	1033769-28-6
SMILES	CC1=C(C=C(C=C1)NC(=O)NC2=C(C=CC(=C2)C(F)(F)F)F)NC3=CC4=C(C=C3)/C(=C/C5=CC=CN5)/C(=O)N4
其他名称	GNF-5837, GNF5837
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	92 mg/mL (171.8 mM)
	Water	Insoluble
	Ethanol	Warmed: 8 mg/mL (14.93 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.67 mL	93.37 mL	186.74 mL
0.5 mM	3.73 mL	18.67 mL	37.35 mL
1 mM	1.87 mL	9.34 mL	18.67 mL
5 mM	0.37 mL	1.87 mL	3.73 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Keywords: 购买 GNF 5837 | GNF 5837 供应商 | GNF 5837 花费 | GNF 5837 生产商 | 订购 GNF 5837 | GNF 5837 代理商 | 购买 1033769-28-6 | 1033769-28-6 供应商 | 1033769-28-6 花费 | 1033769-28-6 生产商 | 订购 1033769-28-6 | 1033769-28-6 代理商