GNF-6231
目录号: A16849
Porcupine 抑制剂
GNF-6231 是一种效力强大的、口服活性的、选择性的 Porcupine 抑制剂，其 IC50 为 0.8 nM。
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生物活性
| Discription | GNF-6231 is a potent, orally active and selective Porcupine inhibitor with IC50 of 0.8 nM. |
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产品信息
| 目录号 | A16849 |
|---|---|
| 分子式 | C24H25FN6O2 |
| 分子量 | 448.49 |
| CAS号 | 1243245-18-2 |
| SMILES | O=C(NC1=NC=C(N2CCN(C(C)=O)CC2)C=C1)CC3=CN=C(C4=CC(F)=NC=C4)C(C)=C3 |
| 其他名称 | GNF6231, GNF 6231 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 87 mg/mL (193.98 mM) | |
| Water | Insoluble | ||
| Ethanol | 5 mg/mL (11.14 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.3 mL | 111.49 mL | 222.97 mL |
| 0.5 mM | 4.46 mL | 22.3 mL | 44.59 mL |
| 1 mM | 2.23 mL | 11.15 mL | 22.3 mL |
| 5 mM | 0.45 mL | 2.23 mL | 4.46 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1243245-18-2 | 1243245-18-2 供应商 | 1243245-18-2 花费 | 1243245-18-2 生产商 | 订购 1243245-18-2 | 1243245-18-2 代理商