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GNF179 metabolite is the metabolite of GNF179, which is an optimized 8,8-dimethyl IP analog that exhibited the potency(4.8 nM against the multidrug resistant strain W2) in vitro metabolic stability and in vivo oral bioavailability.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 40.77 mL | 203.83 mL | 407.66 mL |
| 0.5 mM | 8.15 mL | 40.77 mL | 81.53 mL |
| 1 mM | 4.08 mL | 20.38 mL | 40.77 mL |
| 5 mM | 0.82 mL | 4.08 mL | 8.15 mL |
*The above data is based on the productmolecular weight 245.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21032 |
|---|---|
| M. Wt | 245.3 |
| Formula | C14H16FN3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1310455-86-7 |
| Synonyms | GNF 179, GNF-179 |
| SMILES | CC1(C2=NC(C3=CC=C(F)C=C3)=CN2CCN1)C |
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