GO6983

目录号: A13790

PKC inhibitor

GO6983

GO6983 Chemical Structure

CAS NO. 133053-19-7

GO6983 is a potent protein kinase C (PKC) inhibitor. It reduces polymorphonuclear leukocyte adherence and infiltration following myocardial ischemia/reperfusion injury.

库存: 现货

规格 价格 数量
10 mg
¥ 1,500.00
25 mg
¥ 3,000.00
50 mg
¥ 4,800.00
10mM * 1mL in DMSO
¥ 950.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

GO6983 is a potent protein kinase C (PKC) inhibitor. It reduces polymorphonuclear leukocyte adherence and infiltration following myocardial ischemia/reperfusion injury.
Targets
Target Value
PKCγIC50: 6nM
PKCαIC50: 7nM
PKCβIC50: 7nM
PKCδIC50: 10nM
PKCζIC50: 60nM
PKCμIC50: 20μM
In vitro (25°C) DMSO 59 mg/mL (133.33 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.6 mL 112.99 mL 225.98 mL
0.5 mM 4.52 mL 22.6 mL 45.2 mL
1 mM 2.26 mL 11.3 mL 22.6 mL
5 mM 0.45 mL 2.26 mL 4.52 mL

*The above data is based on the productmolecular weight 442.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A13790
MECHANISM OF ACTION Inhibitor
M. Wt 442.51
Formula C26H26N4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 133053-19-7
Synonyms Go-6983, Go 6983
SMILES CN(C)CCCN1C=C(C2=C1C=CC(=C2)OC)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54

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