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PKC 抑制剂

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产品目录号: A13790


产品名 目录号 价格 数量
GO6983 10mg A13790-10
¥ 1,500.00
GO6983 25mg A13790-25
¥ 3,000.00
GO6983 50mg A13790-50
¥ 4,800.00
GO6983 10mM * 1mL in DMSO A13790-10mM-D
¥ 950.00



GO6983 is a potent protein kinase C (PKC) inhibitor. It reduces polymorphonuclear leukocyte adherence and infiltration following myocardial ischemia/reperfusion injury.





顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A13790
Mechanism of action Inhibitor
分子量 442.51
化学分子式 C26H26N4O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 133053-19-7
Synonyms Go-6983, Go 6983
化学名称 3-(1-(3-(dimethylamino)propyl)-5-methoxy-1H-indol-3-yl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione


GO6983 is a potent protein kinase C (PKC) inhibitor. It reduces polymorphonuclear leukocyte adherence and infiltration following myocardial ischemia/reperfusion injury.
Target Value
PKCγIC50: 6nM
PKCαIC50: 7nM
PKCβIC50: 7nM
PKCδIC50: 10nM
PKCζIC50: 60nM
PKCμIC50: 20μM


Solubility (25°C) * In vitro DMSO 59 mg/mL (133.33 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.6 mL 112.99 mL 225.98mL
0.5 mM 4.52 mL 22.6 mL 45.2 mL
1 mM 2.26 mL 11.3 mL 22.6 mL
5 mM 0.45 mL 2.26 mL 4.52 mL

*The above data is based on the productmolecular weight 442.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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