Golimumab (CNTO-148) is a potent monoclonal antibody of the human IgG1 subclass that functions as a TNF?? antagonist. It exhibits anti-inflammatory properties by inhibiting the production of interleukins IL-6 and IL-1??. The mechanism of action of Golimumab involves targeting and neutralizing tumor necrosis factor (TNF), thereby preventing inflammation and the associated degradation of cartilage and bone. Additionally, Golimumab demonstrates anticancer properties through the induction of cell apoptosis. This antibody is applicable in the research of rheumatoid arthritis, Crohn's disease, and various cancers, providing a valuable tool for both basic research and therapeutic development.
Golimumab (CNTO-148) is a potent monoclonal antibody of the human IgG1 subclass that functions as a TNF?? antagonist. It exhibits anti-inflammatory properties by inhibiting the production of interleukins IL-6 and IL-1??. The mechanism of action of Golimumab involves targeting and neutralizing tumor necrosis factor (TNF), thereby preventing inflammation and the associated degradation of cartilage and bone. Additionally, Golimumab demonstrates anticancer properties through the induction of cell apoptosis. This antibody is applicable in the research of rheumatoid arthritis, Crohn's disease, and various cancers, providing a valuable tool for both basic research and therapeutic development.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
