GS-444217

Name: GS-444217
SKU: A20517
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A20517

ASK1 抑制剂

GS-444217 是一种效力强大的、可口服的、选择性的 ATP 竞争性抑制剂，专门针对凋亡信号调节激酶 1 (ASK1)，其 IC50 为 2.87 nM。

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Grouped product items
规格	价格	库存
1mg	¥245.00	现货
5mg	¥560.00	现货
10mg	¥875.00	现货
25mg	¥1,540.00	现货
50mg	¥2,730.00	现货
100mg	¥4,130.00	现货
*10mM 1mL in DMSO**	¥630.00	现货
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Data Sheet

SDS

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生物活性

Discription

GS-444217 is a potent, orally available and selective ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1) with an IC50 of 2.87 nM.

Targets

Target	Value

产品信息

目录号	A20517
分子式	C23H21N7O
分子量	411.46
CAS号	1262041-49-5
SMILES	O=C(C1=NC=CC(N2C=C(C3CC3)N=C2)=C1)NC4=CC=CC(C5=NN=CN5C6CC6)=C4
其他名称	GS444217, GS 444217
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	55 mg/mL (133.67 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.3 mL	121.52 mL	243.04 mL
0.5 mM	4.86 mL	24.3 mL	48.61 mL
1 mM	2.43 mL	12.15 mL	24.3 mL
5 mM	0.49 mL	2.43 mL	4.86 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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