GS-7340
目录号: A15772
NRT 抑制剂
GS-7340 是替诺福韦(TFV)的前体药物,比替诺福韦二异丙酯更有效地将TFV输送到淋巴细胞和组织中。
| Discription | GS-7340 is a prodrug of tenofovir (TFV) that more efficiently delivers TFV into lymphoid cells and tissues than TFV disoproxil fumarate. | |||||
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| Cell Research |
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| 目录号 | A15772 |
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| 分子式 | C21H29N6O5P |
| 分子量 | 476.47 |
| CAS号 | 379270-37-8 |
| SMILES | CC(C)OC(=O)C(C)NP(=O)(COC(C)CN1C=NC2=C1N=CN=C2N)OC3=CC=CC=C3 |
| 其他名称 | GS7340, GS 7340, Tenofovir alafenamide |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 94 mg/mL (197.28 mM) | |
| Water | Insoluble | ||
| Ethanol | 94 mg/mL (197.28 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.99 mL | 104.94 mL | 209.88 mL |
| 0.5 mM | 4.2 mL | 20.99 mL | 41.98 mL |
| 1 mM | 2.1 mL | 10.49 mL | 20.99 mL |
| 5 mM | 0.42 mL | 2.1 mL | 4.2 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2