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GS-9256

HCV NS3 抑制剂

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产品目录号: A13526

库存状态:中国现货中国现货

产品名 目录号 价格 数量
GS-9256 10mg A13526-10
¥ 1,800.00
GS-9256 25mg A13526-25
¥ 4,000.00
GS-9256 50mg A13526-50
¥ 7,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

GS-9451 is a potent macrocyclic HCV NS3 PI that achieved a median maximal change in HCV RNA of 3.6 log10 IU/mL (range, -4.7 log10 to -3.1 log10 IU/mL) following 3-day monotherapy in treatment-nave patients with HCV genotype 1 infection during phase I.

GS-9256

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Chemical Information

目录号 A13526
Mechanism of action Inhibitor
分子量 957.461
化学分子式 C46H56ClF2N6O8PS
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1001094-46-7
Synonyms GS 9256, GS9256
SMILES code CC(C)NC1=NC(=CS1)C2=NC3=C(C=CC(=C3Cl)OC)C(=C2)O[C@@H]4C[C@H]5C(=O)N[C@@]6(C[C@H]6CCCCCCC[C@@H](C(=O)N5C4)NC(=O)OC7CCCC7)P(=O)(CC8=C(C=CC=C8F)F)O
化学名称 N/A

生物活性

Description
GS-9451 is a potent macrocyclic HCV NS3 PI that achieved a median maximal change in HCV RNA of 3.6 log10 IU/mL (range, -4.7 log10 to -3.1 log10 IU/mL) following 3-day monotherapy in treatment-nave patients with HCV genotype 1 infection during phase I.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 10.44 mL 52.22 mL 104.44mL
0.5 mM 2.09 mL 10.44 mL 20.89 mL
1 mM 1.04 mL 5.22 mL 10.44 mL
5 mM 0.21 mL 1.04 mL 2.09 mL

*The above data is based on the productmolecular weight 957.461. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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