GS-9256

目录号: A13526

HCV NS3 inhibitor

GS-9256 Chemical Structure

CAS NO. 1001094-46-7

GS-9451 is a potent macrocyclic HCV NS3 PI that achieved a median maximal change in HCV RNA of 3.6 log10 IU/mL (range, -4.7 log10 to -3.1 log10 IU/mL) following 3-day monotherapy in treatment-nave patients with HCV genotype 1 infection during phase I.

库存: 现货

规格 价格 数量
10 mg
¥ 1,800.00
25 mg
¥ 4,000.00
50 mg
¥ 7,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

GS-9451 is a potent macrocyclic HCV NS3 PI that achieved a median maximal change in HCV RNA of 3.6 log10 IU/mL (range, -4.7 log10 to -3.1 log10 IU/mL) following 3-day monotherapy in treatment-nave patients with HCV genotype 1 infection during phase I.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 10.44 mL 52.22 mL 104.44 mL
0.5 mM 2.09 mL 10.44 mL 20.89 mL
1 mM 1.04 mL 5.22 mL 10.44 mL
5 mM 0.21 mL 1.04 mL 2.09 mL

*The above data is based on the productmolecular weight 957.461. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A13526
MECHANISM OF ACTION Inhibitor
M. Wt 957.461
Formula C46H56ClF2N6O8PS
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1001094-46-7
Synonyms GS 9256, GS9256
SMILES CC(C)NC1=NC(=CS1)C2=NC3=C(C=CC(=C3Cl)OC)C(=C2)O[C@@H]4C[C@H]5C(=O)N[C@@]6(C[C@H]6CCCCCCC[C@@H](C(=O)N5C4)NC(=O)OC7CCCC7)P(=O)(CC8=C(C=CC=C8F)F)O

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