GS-9256
目录号: A13526
HCV NS3 抑制剂
GS-9451 是一种强效的环状 HCV NS3 PI,在第一阶段临床试验中,对 HCV 基因型 1 感染的未经治疗的患者进行了3天的单药治疗后,其 HCV RNA 的中位数最大变化达到了 3.6 log10 IU/mL(范围从 -4.7 log10 到 -3.1 log10 IU/mL)。
| Discription | GS-9451 is a potent macrocyclic HCV NS3 PI that achieved a median maximal change in HCV RNA of 3.6 log10 IU/mL (range, -4.7 log10 to -3.1 log10 IU/mL) following 3-day monotherapy in treatment-nave patients with HCV genotype 1 infection during phase I. |
|---|
| 目录号 | A13526 |
|---|---|
| 分子式 | C46H56ClF2N6O8PS |
| 分子量 | 957.461 |
| CAS号 | 1001094-46-7 |
| SMILES | CC(C)NC1=NC(=CS1)C2=NC3=C(C=CC(=C3Cl)OC)C(=C2)O[C@@H]4C[C@H]5C(=O)N[C@@]6(C[C@H]6CCCCCCC[C@@H](C(=O)N5C4)NC(=O)OC7CCCC7)P(=O)(CC8=C(C=CC=C8F)F)O |
| 其他名称 | GS 9256, GS9256 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2