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GS-9901 is a highly selective and orally active PI3Kδ inhibitor, with an IC50 of 1 nM. Has potential to treat rheumatoid arthritis.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.93 mL | 104.63 mL | 209.26 mL |
| 0.5 mM | 4.19 mL | 20.93 mL | 41.85 mL |
| 1 mM | 2.09 mL | 10.46 mL | 20.93 mL |
| 5 mM | 0.42 mL | 2.09 mL | 4.19 mL |
*The above data is based on the productmolecular weight 477.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12988 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 477.88 |
| Formula | C22H17ClFN9O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1640247-87-5 |
| Synonyms | GS9901, GS 9901 |
| SMILES | NC1=NC(N)=NC(N[C@H](C2CC2)C(N3C4=CN=CC=C4)=NC5=C(F)C=CC(Cl)=C5C3=O)=C1C#N |
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