产品详情

生物活性

GS967是一种新型的，有效的，选择性的心脏晚期钠电流抑制剂（INa晚期）；抑制心室肌细胞和离体心脏中ATX-II诱导的晚期I（Na），IC（50）值分别为0.13和0.21 uM。

溶解度 *

In vitro	DMSO	38 mg/mL (109.44 mM)
	Water	Insoluble
	Ethanol	39 mg/mL (112.32 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	28.8 mL	144 mL	288 mL
0.5 mM	5.76 mL	28.8 mL	57.6 mL
1 mM	2.88 mL	14.4 mL	28.8 mL
5 mM	0.58 mL	2.88 mL	5.76 mL

*The above data is based on the productmolecular weight 347.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A14361
作用机制	Inhibitor (抑制剂)
M. Wt	347.22
Formula	C14H7F6N3O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1262618-39-2
Synonyms	GS-967, GS 967
SMILES	FC(F)(F)C1=NN=C2C=CC(C3=CC=C(OC(F)(F)F)C=C3)=CN21