GSK 1210151A (I-BET151)

目录号: A11783

BET Bromodomain 抑制剂

GSK 1210151A (I-BET151)

GSK 1210151A (I-BET151) Chemical Structure

CAS NO. 1300031-49-5

GSK 1210151A (I-BET151)是溴结构域和额外末端(BET)家族蛋白BRD2,BRD3和BRD4的新型选择性抑制剂。

库存: 现货

规格 价格 数量
5 mg
¥ 800.00
10 mg
¥ 1,200.00
25 mg
¥ 2,000.00
50 mg
¥ 3,600.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

GSK 1210151A (I-BET151)是溴结构域和额外末端(BET)家族蛋白BRD2,BRD3和BRD4的新型选择性抑制剂。
靶点信息
BRD3 (Cell-free assay) BRD2 (Cell-free assay) BRD4 (Cell-free assay)
0.25 μM0.5 μM0.79 μM
In vitro DMSO <1 mg/mL (<1 mM)
Water <1 mg/mL (<1 mM)
Ethanol 27 mg/mL (64.99 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.07 mL 120.37 mL 240.73 mL
0.5 mM 4.81 mL 24.07 mL 48.15 mL
1 mM 2.41 mL 12.04 mL 24.07 mL
5 mM 0.48 mL 2.41 mL 4.81 mL

*The above data is based on the productmolecular weight 415.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11783
作用机制 Inhibitor (抑制剂)
M. Wt 415.4
Formula C23H21N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1300031-49-5
Synonyms GSK1210151A
SMILES CC1=C(C(=NO1)C)C2=C(C=C3C(=C2)N=CC4=C3N(C(=O)N4)[C@H](C)C5=CC=CC=N5)OC

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