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GSK-2033是有效的细胞活性LXR拮抗剂（pIC50 = 7.5）。它增强T细胞增殖并阻断T 0901317对T细胞的抗增殖活性，并且具有细胞渗透性。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.9 mL | 84.51 mL | 169.02 mL |
| 0.5 mM | 3.38 mL | 16.9 mL | 33.8 mL |
| 1 mM | 1.69 mL | 8.45 mL | 16.9 mL |
| 5 mM | 0.34 mL | 1.69 mL | 3.38 mL |
*The above data is based on the productmolecular weight 591.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A17017 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 591.66 |
| Formula | C29H28F3NO5S2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1221277-90-2 |
| Synonyms | GSK2033, GSK 2033 |
| SMILES | O=S(C1=C(C)C=C(C)C=C1C)(N(CC2=CC=C(C3=CC=CC(S(=O)(C)=O)=C3)C=C2)CC4=CC=C(C(F)(F)F)O4)=O |
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