GSK-2193874

Name: GSK-2193874
SKU: A14201
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A14201

TRPV4 blocker

GSK2193874 被确认为一种选择性的、口服活性的 TRPV4 阻断剂，它能抑制通过重组 TRPV4 通道和天然内皮 TRPV4 电流的 Ca(2+) 流入。

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Grouped product items
规格	价格	库存
1mg	¥210.00	现货
2mg	¥315.00	现货
5mg	¥455.00	现货
10mg	¥840.00	现货
25mg	¥1,750.00	现货
50mg	¥2,940.00	现货
100mg	¥4,375.00	现货
*10mM 1mL in DMSO**	¥735.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

GSK2193874 was identified as a selective, orally active TRPV4 blocker that inhibits Ca(2+) influx through recombinant TRPV4 channels and native endothelial TRPV4 currents.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A14201
分子式	C37H38BrF3N4O
分子量	691.62
CAS号	1336960-13-4
SMILES	C1CCN(CC1)C2CCN(CC2)CC3=C(N=C4C=C(C=CC4=C3C(=O)NC5(CC5)C6=CC=CC=C6)Br)C7=CC(=CC=C7)C(F)(F)F
其他名称	GSK 2193874, GSK2193874
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	95 mg/mL (137.35 mM)
	Water	Insoluble
	Ethanol	Warmed: 48 mg/mL (69.4 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	14.46 mL	72.29 mL	144.59 mL
0.5 mM	2.89 mL	14.46 mL	28.92 mL
1 mM	1.45 mL	7.23 mL	14.46 mL
5 mM	0.29 mL	1.45 mL	2.89 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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