GSK 2250665A

Name: GSK 2250665A
SKU: A17191

目录号: A17191

Itk 抑制剂

GSK 2250665A Chemical Structure

CAS NO. 1246030-96-5

GSK-2250665A是pKi = 9.2的Itk抑制剂，它对Aurora B激酶和Btk（pIC50值分别为6.4和6.5）和一组其他激酶表现出对Itk的选择性。抑制PBMC中IFNγ的产生。

库存：现货

规格	价格	数量
5 mg	￥ 1,000.00
10 mg	￥ 1,800.00
50 mg	￥ 5,400.00
100 mg	￥ 9,200.00

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生物活性

GSK-2250665A是pKi = 9.2的Itk抑制剂，它对Aurora B激酶和Btk（pIC50值分别为6.4和6.5）和一组其他激酶表现出对Itk的选择性。抑制PBMC中IFNγ的产生。

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.76 mL	108.79 mL	217.58 mL
0.5 mM	4.35 mL	21.76 mL	43.52 mL
1 mM	2.18 mL	10.88 mL	21.76 mL
5 mM	0.44 mL	2.18 mL	4.35 mL

*The above data is based on the productmolecular weight 459.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A17191
作用机制	Inhibitor (抑制剂)
M. Wt	459.61
Formula	C26H29N5OS
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1246030-96-5
Synonyms	GSK2250665A, GSK-2250665A
SMILES	CCC1=CC=C(N=C(NC3=NC(N[C@H]5CC[C@H](O)CC5)=NC(CC4=CC=CC=C4)=C3)S2)C2=C1