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GSK 2250665A

目录号: A17191
Itk 抑制剂
GSK-2250665A 是一种 Itk 抑制剂,具有 pKi 值为 9.2,它对 Itk 比对 Aurora B 激酶和 Btk 显示出选择性(pIC50 值分别为 6.4 和 6.5),并且对其他一系列激酶也有抑制作用。该抑制剂能够抑制 PBMCs 中的 IFNγ 产生。
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规格 价格 库存 数量
5mg
¥665.00
现货
10mg
¥1,225.00
现货
50mg
¥3,745.00
现货
100mg
¥6,405.00
现货
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生物活性
Discription GSK-2250665A is a Itk inhibitor with pKi = 9.2, it Exhibits selectivity for Itk over Aurora B kinase and Btk (pIC50 values are 6.4 and 6.5, respectively) and a panel of other kinases. Inhibits IFNγ production in PBMCs.
产品信息
目录号 A17191
分子式 C26H29N5OS
分子量 459.61
CAS号 1246030-96-5
SMILES CCC1=CC=C(N=C(NC3=NC(N[C@H]5CC[C@H](O)CC5)=NC(CC4=CC=CC=C4)=C3)S2)C2=C1
其他名称 GSK2250665A, GSK-2250665A
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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