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GSK 2334470

促销

PDK1 抑制剂

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产品目录号: A12767

库存状态:中国现货中国现货

产品名 目录号 价格 数量
GSK 2334470 10mg A12767-10
¥ 900.00
GSK 2334470 25mg A12767-25
¥ 1,800.00
GSK 2334470 50mg A12767-50
¥ 3,000.00
GSK 2334470 100mg A12767-100
¥ 5,000.00
GSK 2334470 10mM * 1mL in DMSO A12767-10mM-D
¥ 1,010.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

GSK 2334470 is a potent 3-phosphoinositide-dependent protein kinase (PDK1) inhibitor (IC50 ~ 10 nM).

GSK 2334470

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Chemical Information

目录号 A12767
Mechanism of action Inhibitor
分子量 462.59
化学分子式 C25H34N8O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1227911-45-6
Synonyms GSK-2334470, GSK2334470
SMILES code C[C@@H]1CC[C@@H](CN1C2=NC(=NC(=C2)C3=CC4=C(C=C3)C(=NN4)N)NC)C(=O)NC5CCCCC5
化学名称 (3S,6R)-1-[6-(3-Amino-1H-indazol-6-?yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-6-?methyl-3-piperidinecarboxamide

生物活性

Description
GSK 2334470 is a potent 3-phosphoinositide-dependent protein kinase (PDK1) inhibitor (IC50 ~ 10 nM).
Targets
PDK-1 (Cell-free assay)
10 nM

溶解性

Solubility (25°C)* In vitro DMSO 90 mg/mL (194.55 mM)
Water <1 mg/mL (<1 mM)
Ethanol 90 mg/mL (194.55 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.62 mL 108.09 mL 216.17mL
0.5 mM 4.32 mL 21.62 mL 43.23 mL
1 mM 2.16 mL 10.81 mL 21.62 mL
5 mM 0.43 mL 2.16 mL 4.32 mL

*The above data is based on the productmolecular weight 462.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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