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GSK 2334470


PDK1 抑制剂

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产品目录号: A12767


产品名 目录号 价格 数量
GSK 2334470 10mg A12767-10
¥ 900.00
GSK 2334470 25mg A12767-25
¥ 1,800.00
GSK 2334470 50mg A12767-50
¥ 3,000.00
GSK 2334470 100mg A12767-100
¥ 5,000.00
GSK 2334470 10mM * 1mL in DMSO A12767-10mM-D
¥ 1,010.00



GSK 2334470 is a potent 3-phosphoinositide-dependent protein kinase (PDK1) inhibitor (IC50 ~ 10 nM).

GSK 2334470




顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A12767
Mechanism of action Inhibitor
分子量 462.59
化学分子式 C25H34N8O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1227911-45-6
Synonyms GSK-2334470, GSK2334470
SMILES code C[C@@H]1CC[C@@H](CN1C2=NC(=NC(=C2)C3=CC4=C(C=C3)C(=NN4)N)NC)C(=O)NC5CCCCC5
化学名称 (3S,6R)-1-[6-(3-Amino-1H-indazol-6-?yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-6-?methyl-3-piperidinecarboxamide


GSK 2334470 is a potent 3-phosphoinositide-dependent protein kinase (PDK1) inhibitor (IC50 ~ 10 nM).
PDK-1 (Cell-free assay)
10 nM


Solubility (25°C)* In vitro DMSO 90 mg/mL (194.55 mM)
Water <1 mg/mL (<1 mM)
Ethanol 90 mg/mL (194.55 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.62 mL 108.09 mL 216.17mL
0.5 mM 4.32 mL 21.62 mL 43.23 mL
1 mM 2.16 mL 10.81 mL 21.62 mL
5 mM 0.43 mL 2.16 mL 4.32 mL

*The above data is based on the productmolecular weight 462.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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