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GSK 269962

ROCK inhibotor

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产品目录号: A12348

库存状态:中国现货中国现货

产品名 目录号 价格 数量
GSK 269962 5mg A12348-5
¥ 800.00
GSK 269962 10mg A12348-10
¥ 1,500.00
GSK 269962 25mg A12348-25
¥ 3,500.00
GSK 269962 50mg A12348-50
¥ 6,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

GSK 269962 is a potent Rho kinase (ROCK) inhibitor (IC50 values are 1.6 and 4 nM for recombinant human ROCK1 and ROCK2 respectively).

GSK 269962

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顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 GSK 269962 发表的文献 (1)
  • Praneeth Siripurapu, .et al. Two independent but synchronized G汕污 subunit每controlled pathways are essential for trailing-edge retraction during macrophage migration, J Biol Chem, 2017, Oct 20; 292(42): 17482每17495 PMID: 28864771

Chemical Information

目录号 A12348
Mechanism of action Inhibitor
分子量 570.6
化学分子式 C29H30N8O5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 850664-21-0
Synonyms GSK269962,GSK-269962, GSK269962A, GSK-269962A
SMILES code CCN1C2=CC(=NC=C2N=C1C3=NON=C3N)OC4=CC=CC(=C4)NC(=O)C5=CC=C(C=C5)OCCN6CCOCC6
化学名称 N-[3-[[2-(4-Amino-1,2,5-oxadiazol-3?-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy]phe?nyl]-4-[2-(4-morpholinyl)ethoxy]benzamide

生物活性

Description
GSK 269962 is a potent Rho kinase (ROCK) inhibitor (IC50 values are 1.6 and 4 nM for recombinant human ROCK1 and ROCK2 respectively).

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.53 mL 87.63 mL 175.25mL
0.5 mM 3.51 mL 17.53 mL 35.05 mL
1 mM 1.75 mL 8.76 mL 17.53 mL
5 mM 0.35 mL 1.75 mL 3.51 mL

*The above data is based on the productmolecular weight 570.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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