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PPAR 拮抗剂

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产品目录号: A12391


产品名 目录号 价格 数量
GSK-3787 10mg A12391-10
¥ 700.00
GSK-3787 25mg A12391-25
¥ 1,400.00
GSK-3787 50mg A12391-50
¥ 2,200.00
GSK-3787 100mg A12391-100
¥ 3,800.00
GSK-3787 10mM * 1mL in DMSO A12391-10mM-D
¥ 860.00



GSK-3787 is a potent and selective peroxisome proliferator-activated receptor δ (PPARδ) antagonist (pIC50 = 6.6).





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Chemical Information

目录号 A12391
Mechanism of action Antagonist
分子量 392.78
化学分子式 C15H12ClF3N2O3S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 188591-46-0
Synonyms GSK3787, GSK 3787
SMILES code C1=CC(=CC=C1C(=O)NCCS(=O)(=O)C2=NC=C(C=C2)C(F)(F)F)Cl
化学名称 4-Chloro-N-[2-[[5-(trifluoromethyl)?-2-pyridinyl]sulfonyl]ethyl]benzamide


GSK-3787 is a potent and selective peroxisome proliferator-activated receptor δ (PPARδ) antagonist (pIC50 = 6.6).


Solubility (25°C)* In vitro DMSO 79 mg/mL (201.13 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.46 mL 127.3 mL 254.6mL
0.5 mM 5.09 mL 25.46 mL 50.92 mL
1 mM 2.55 mL 12.73 mL 25.46 mL
5 mM 0.51 mL 2.55 mL 5.09 mL

*The above data is based on the productmolecular weight 392.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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