Anti-PVRIG (GSK4381562) is a human monoclonal antibody of the immunoglobulin G1 (IgG1) class, targeting the poliovirus receptor-related immunoglobulin domain-containing protein (PVRIG, also known as CD112R). This antibody is designed to modulate immune response through its inhibitory effects on the PVRIG pathway, which is implicated in immune checkpoint regulation. The interaction between Anti-PVRIG and its target has the potential to enhance antitumor immune activity by alleviating immune suppression in the tumor microenvironment, thereby offering therapeutic benefits in oncology research and treatment.
Anti-PVRIG (GSK4381562) is a human monoclonal antibody of the immunoglobulin G1 (IgG1) class, targeting the poliovirus receptor-related immunoglobulin domain-containing protein (PVRIG, also known as CD112R). This antibody is designed to modulate immune response through its inhibitory effects on the PVRIG pathway, which is implicated in immune checkpoint regulation. The interaction between Anti-PVRIG and its target has the potential to enhance antitumor immune activity by alleviating immune suppression in the tumor microenvironment, thereby offering therapeutic benefits in oncology research and treatment.
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