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GSK 525762A (I-BET-762)

促销

BET 抑制剂

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产品目录号: A11440

库存状态:中国现货中国现货

产品名 目录号 价格 数量
GSK 525762A 5mg A11440-5
¥ 800.00
GSK 525762A 10mg A11440-10
¥ 1,200.00
GSK 525762A 25mg A11440-25
¥ 2,400.00
GSK 525762A 50mg A11440-50
¥ 3,600.00
GSK 525762A (I-BET-762) 10mM * 1mL in DMSO A11440-10mM-D
¥ 900.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

GSK-525762A is a small molecule inhibitor of the BET (Bromodomain and Extra-Terminal) family

GSK 525762A (I-BET-762)

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Chemical Information

目录号 A11440
Mechanism of action Inhibitor
分子量 423.9
化学分子式 C22H22ClN5O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1260907-17-2
Synonyms GSK-525762A, GSK525762A
SMILES code CCNC(=O)C[C@H]1C2=NN=C(N2C3=C(C=C(C=C3)OC)C(=N1)C4=CC=C(C=C4)Cl)C
化学名称 (4S)-6-(4-Chlorophenyl)-N-ethyl-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-acetamide

生物活性

Description
GSK-525762A is a small molecule inhibitor of the BET (Bromodomain and Extra-Terminal) family
Targets
BET proteins (Cell-free assay)
35 nM

溶解性

Solubility (25°C)* In vitro DMSO 84 mg/mL (198.15 mM)
Water <1 mg/mL (<1 mM)
Ethanol 84 mg/mL (198.15 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.59 mL 117.95 mL 235.9mL
0.5 mM 4.72 mL 23.59 mL 47.18 mL
1 mM 2.36 mL 11.8 mL 23.59 mL
5 mM 0.47 mL 2.36 mL 4.72 mL

*The above data is based on the productmolecular weight 423.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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