GSK-872
目录号: A19871
RIPK3 抑制剂
GSK-872 是一种 RIPK3 抑制剂，它与 RIP3 激酶结构域 结合的 IC50 为 1.8 nM，并且抑制激酶活性的 IC50 为 1.3 nM。
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生物活性
| Discription | GSK-872 is a RIPK3 inhibitor, which binds RIP3 kinase domain with an IC50 of 1.8 nM, and inhibits kinase activity with an IC50 of 1.3 nM. | |||||
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| Cell Research |
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产品信息
| 目录号 | A19871 |
|---|---|
| 分子式 | C19H17N3O2S2 |
| 分子量 | 383.49 |
| CAS号 | 1346546-69-7 |
| SMILES | O=S(C1=CC=C2N=CC=C(NC3=CC=C(SC=N4)C4=C3)C2=C1)(C(C)C)=O |
| 其他名称 | GSK 872, GSK872 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 73 mg/mL (190.35 mM) | |
| Water | Insoluble | ||
| Ethanol | 38 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.08 mL | 130.38 mL | 260.76 mL |
| 0.5 mM | 5.22 mL | 26.08 mL | 52.15 mL |
| 1 mM | 2.61 mL | 13.04 mL | 26.08 mL |
| 5 mM | 0.52 mL | 2.61 mL | 5.22 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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