GSK1016790A
目录号: A15854
TRPV4 Activator
GSK1016790A 是一种新型、高效的 TRPV4 (瞬时受体电位香草酸4) 激活剂,其在脉络丛上皮细胞中的 EC50 为 34nM。
| Discription | GSK1016790A is a novel, potent activator of TRPV4 (transient receptor potential vanilloid 4) with EC50 of 34nM in choroid plexus epithelial cells. | |||||
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| 目录号 | A15854 |
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| 分子式 | C28H32Cl2N4O6S2 |
| 分子量 | 655.61 |
| CAS号 | 942206-85-1 |
| SMILES | CC(C)CC(C(=O)N1CCN(CC1)C(=O)C(CO)NS(=O)(=O)C2=C(C=C(C=C2)Cl)Cl)NC(=O)C3=CC4=CC=CC=C4S3 |
| 其他名称 | GSK101 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 98 mg/mL (149.47 mM) | |
| Water | Insoluble | ||
| Ethanol | 98 mg/mL (149.47 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 15.25 mL | 76.26 mL | 152.53 mL |
| 0.5 mM | 3.05 mL | 15.25 mL | 30.51 mL |
| 1 mM | 1.53 mL | 7.63 mL | 15.25 mL |
| 5 mM | 0.31 mL | 1.53 mL | 3.05 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2