GSK1070916

Name: GSK1070916
SKU: A11168
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A11168

Aurora Kinase B/C 抑制剂

GSK1070916 是一种强效的 Aurora B/C 激酶抑制剂（IC50 为 3.5 nM/6.5 nM），在组织培养细胞和人类肿瘤异种移植模型中具有广泛的抗肿瘤活性。

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Grouped product items
规格	价格	库存
1mg	¥245.00	现货
5mg	¥595.00	现货
10mg	¥1,015.00	现货
25mg	¥1,890.00	现货
50mg	¥2,765.00	现货
100mg	¥4,480.00	现货
*10mM 1mL in DMSO**	¥665.00	现货
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Data Sheet

SDS

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生物活性

Discription

GSK1070916 is a potent Aurora B/C kinase inhibitor (with IC50 of 3.5 nM/6.5 nM) with broad antitumor activity in tissue culture cells and human tumor xenograft models.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11168
分子式	C30H33N7O
分子量	507.63
CAS号	942918-07-2
SMILES	CCN1C=C(C(=N1)C2=CC=C(C=C2)NC(=O)N(C)C)C3=C4C=C(NC4=NC=C3)C5=CC(=CC=C5)CN(C)C
其他名称	GSK-1070916
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	91 mg/mL (179.26 mM)
	Water	Insoluble
	Ethanol	8 mg/mL (15.75 mM)
In vivo	2% Cremophor EL, 2% N,N-dimethylacetamide, pH 5.0	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.7 mL	98.5 mL	196.99 mL
0.5 mM	3.94 mL	19.7 mL	39.4 mL
1 mM	1.97 mL	9.85 mL	19.7 mL
5 mM	0.39 mL	1.97 mL	3.94 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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