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GSK180 is a selective, competitive, and potent inhibitor of kynurenine-3-monooxygenase (KMO), a key enzyme of tryptophan metabolism (IC50, ~6 nM), but shows negligible activity against other enzymes on the tryptophan pathway.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 36.22 mL | 181.11 mL | 362.23 mL |
| 0.5 mM | 7.24 mL | 36.22 mL | 72.45 mL |
| 1 mM | 3.62 mL | 18.11 mL | 36.22 mL |
| 5 mM | 0.72 mL | 3.62 mL | 7.24 mL |
*The above data is based on the productmolecular weight 276.07. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A19923 |
|---|---|
| M. Wt | 276.07 |
| Formula | C10H7Cl2NO4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1799725-26-0 |
| Synonyms | GSK 180; GSK-180 |
| SMILES | O=C(O)CCN1C(OC2=CC(Cl)=C(Cl)C=C12)=O |
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