GSK180
目录号: A19923
KMO 抑制剂
GSK180 是一种选择性、竞争性和强效的 犬尿氨酸-3-单加氧酶(KMO)抑制剂,这是色氨酸代谢中的关键酶(IC50约为6 nM),但对色氨酸途径上的其他酶几乎没有活性。
Discription | GSK180 is a selective, competitive, and potent inhibitor of kynurenine-3-monooxygenase (KMO), a key enzyme of tryptophan metabolism (IC50, ~6 nM), but shows negligible activity against other enzymes on the tryptophan pathway. |
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目录号 | A19923 |
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分子式 | C10H7Cl2NO4 |
分子量 | 276.07 |
CAS号 | 1799725-26-0 |
SMILES | O=C(O)CCN1C(OC2=CC(Cl)=C(Cl)C=C12)=O |
其他名称 | GSK 180; GSK-180 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2