GSK2141795 (Uprosertib, GSK795)

Name: GSK2141795 (Uprosertib, GSK795)
SKU: A15809
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A15809

Akt 抑制剂

Akt 抑制剂 GSK2141795 与 Akt 结合并抑制其活性，这可能导致抑制 PI3K/Akt 信号通路和肿瘤细胞增殖，并诱导肿瘤细胞凋亡。

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Grouped product items
规格	价格	库存
1mg	¥210.00	现货
2mg	¥315.00	现货
5mg	¥490.00	现货
10mg	¥840.00	现货
25mg	¥1,435.00	现货
50mg	¥2,345.00	现货
100mg	¥3,885.00	现货
200mg	¥5,495.00	现货
*10mM 1mL in DMSO**	¥735.00	现货
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Data Sheet

SDS

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生物活性

Discription

Akt inhibitor GSK2141795 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A15809
分子式	C18H16Cl2F2N4O2
分子量	429.25
CAS号	1047634-65-0
SMILES	CN1C(=C(C=N1)Cl)C2=C(OC(=C2)C(=O)NC(CC3=CC(=C(C=C3)F)F)CN)Cl
其他名称	GSK2141795, GSK2141795, Uprosertib, GSK 795
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	80 mg/mL (186.36 mM)
	Water	Insoluble
	Ethanol	80 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.3 mL	116.48 mL	232.96 mL
0.5 mM	4.66 mL	23.3 mL	46.59 mL
1 mM	2.33 mL	11.65 mL	23.3 mL
5 mM	0.47 mL	2.33 mL	4.66 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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