GSK2141795 (Uprosertib, GSK795)

目录号: A15809

Akt inhibitor

GSK2141795 (Uprosertib, GSK795)

GSK2141795 (Uprosertib, GSK795) Chemical Structure

CAS NO. 1047634-65-0

Akt inhibitor GSK2141795 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis.

库存: 现货

规格 价格 数量
5 mg
¥ 1,000.00
10 mg
¥ 1,500.00
25 mg
¥ 3,700.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Akt inhibitor GSK2141795 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis.
Targets
Akt3 Akt1 Akt2
38 nM180 nM328 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.3 mL 116.48 mL 232.96 mL
0.5 mM 4.66 mL 23.3 mL 46.59 mL
1 mM 2.33 mL 11.65 mL 23.3 mL
5 mM 0.47 mL 2.33 mL 4.66 mL

*The above data is based on the productmolecular weight 429.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A15809
MECHANISM OF ACTION Inhibitor
M. Wt 429.25
Formula C18H16Cl2F2N4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1047634-65-0
Synonyms GSK2141795, GSK2141795, Uprosertib, GSK 795
SMILES CN1C(=C(C=N1)Cl)C2=C(OC(=C2)C(=O)NC(CC3=CC(=C(C=C3)F)F)CN)Cl

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