产品详情
GSK2256294A is a potent, reversible, tight binding inhibitor of isolated recombinant human sEH (soluble epoxide hydrolase) (IC50 = 27 pM; t1/2 = 121 min) and displays potent inhibition against the rat (IC50 = 61 pM) and murine (IC50 = 189 pM) orthologs of sEH.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22.35 mL | 111.74 mL | 223.48 mL |
0.5 mM | 4.47 mL | 22.35 mL | 44.7 mL |
1 mM | 2.23 mL | 11.17 mL | 22.35 mL |
5 mM | 0.45 mL | 2.23 mL | 4.47 mL |
*The above data is based on the productmolecular weight 447.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A20696 |
---|---|
M. Wt | 447.46 |
Formula | C21H24F3N7O |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1142090-23-0 |
Synonyms | GSK-2256294A, GSK 2256294A, GSK 2256294, GSK-2256294, GSK2256294 |
SMILES | O=C([C@H]1C[C@@H](NC2=NC(NC)=NC(C)=N2)CCC1)NCC3=CC=C(C#N)C=C3C(F)(F)F |
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