GSK256066 2,2,2-trifluoroacetic acid
目录号: A15097
PDE 抑制剂
GSK256066 是一种选择性的 PDE4B(对A-D亚型具有相同的亲和力)抑制剂,其 IC50 为3.2 pM,对 PDE1/2/3/5/6 的选择性超过380,000倍,与 PDE7 相比对 PDE4B 的选择性超过2500倍。
Discription | GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380,000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold selectivity against PDE4B versus PDE7. |
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目录号 | A15097 |
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分子式 | C29H27F3N4O7S |
分子量 | 632.61 |
CAS号 | 1415560-64-3 |
SMILES | CC1=C2C(=CC(=C1)S(=O)(=O)C3=CC=CC(=C3)C(=O)N(C)C)C(=C(C=N2)C(=O)N)NC4=CC(=CC=C4)OC.C(=O)(C(F)(F)F)O |
其他名称 | GSK-256066, GSK 256066 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2