GSK256066 2,2,2-trifluoroacetic acid

目录号: A15097

PDE Inhibitor

GSK256066 2,2,2-trifluoroacetic acid Chemical Structure

CAS NO. 1415560-64-3

GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380,000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold selectivity against PDE4B versus PDE7.

库存: 现货

规格 价格 数量
10 mg
¥ 2,000.00
50 mg
¥ 6,000.00
500 mg
¥ 17,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380,000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold selectivity against PDE4B versus PDE7.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.81 mL 79.04 mL 158.08 mL
0.5 mM 3.16 mL 15.81 mL 31.62 mL
1 mM 1.58 mL 7.9 mL 15.81 mL
5 mM 0.32 mL 1.58 mL 3.16 mL

*The above data is based on the productmolecular weight 632.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15097
MECHANISM OF ACTION Inhibitor
M. Wt 632.61
Formula C29H27F3N4O7S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1415560-64-3
Synonyms GSK-256066, GSK 256066
SMILES CC1=C2C(=CC(=C1)S(=O)(=O)C3=CC=CC(=C3)C(=O)N(C)C)C(=C(C=N2)C(=O)N)NC4=CC(=CC=C4)OC.C(=O)(C(F)(F)F)O

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