GSK256066

目录号: A11073

PDE 抑制剂

GSK256066

GSK256066 Chemical Structure

CAS NO. 801312-28-7

GSK256066是PDE4的极高亲和力和选择性抑制剂,它以相等的亲和力抑制PDE4亚型A-D,并具有很高的HARBS(高亲和力利普兰结合位点)比率(> 17)。

库存: 现货

规格 价格 数量
5 mg
¥ 1,200.00
10 mg
¥ 2,200.00
50 mg
¥ 6,000.00
100 mg
¥ 9,800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

GSK256066是PDE4的极高亲和力和选择性抑制剂,它以相等的亲和力抑制PDE4亚型A-D,并具有很高的HARBS(高亲和力利普兰结合位点)比率(> 17)。
靶点信息
PDE4B
3.2 pM
In vitro (25°C) DMSO 4 mg/mL (7.71 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.28 mL 96.41 mL 192.83 mL
0.5 mM 3.86 mL 19.28 mL 38.57 mL
1 mM 1.93 mL 9.64 mL 19.28 mL
5 mM 0.39 mL 1.93 mL 3.86 mL

*The above data is based on the productmolecular weight 518.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11073
作用机制 Inhibitor (抑制剂)
M. Wt 518.6
Formula C27H26N4O5S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 801312-28-7
Synonyms GSK-256066
SMILES CC1=C2C(=CC(=C1)S(=O)(=O)C3=CC=CC(=C3)C(=O)N(C)C)C(=C(C=N2)C(=O)N)NC4=CC(=CC=C4)OC

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