|Mechanism of action||Inhibitor|
|储存方式||at -20°C 2 years|
|GSK256066 is an exceptionally high affinity and selective inhibitor of PDE4 that inhibits PDE4 isoforms A-D with equal affinity and has a high HARBS (High-Affinity Rolipram Binding Site) ratio (>17).|
|Solubility (25°C) *||In vitro||DMSO||5 mg/mL (9.64 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||<1 mg/mL (<1 mM)|
|In vivo||30% propylene glycol, 5% Tween 80, 65% D5W||30 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||19.28 mL||96.41 mL||192.83mL|
|0.5 mM||3.86 mL||19.28 mL||38.57 mL|
|1 mM||1.93 mL||9.64 mL||19.28 mL|
|5 mM||0.39 mL||1.93 mL||3.86 mL|
*The above data is based on the productmolecular weight 518.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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