GSK2795039
目录号: A20998
NOX2 抑制剂
GSK2795039 是一种 NADPH 氧化酶 2（NOX2）抑制剂，在不同的无细胞测试中具有平均 pIC50 值为 6。GSK2795039 抑制活性氧（ROS）的产生和 NADPH 的消耗。GSK2795039 减少细胞凋亡。
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生物活性
| Discription | GSK2795039 is a NADPH oxidase 2 (NOX2) inhibitor with a mean pIC50 of 6 in different cell-free assays. GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 reduces apoptosis. |
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产品信息
| 目录号 | A20998 |
|---|---|
| 分子式 | C23H26N6O2S |
| 分子量 | 450.56 |
| CAS号 | 1415925-18-6 |
| SMILES | CC(C)N1C=C(C2=CC=C(CCN3C)C3=C2)C4=C1N=CC=C4NS(C5=NN(C)C=C5)(=O)=O |
| 其他名称 | GSK 2795039, GSK-2795039 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 80 mg/mL (177.56 mM) | |
| Water | Insoluble | ||
| Ethanol | 18 mg/mL (39.94 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.19 mL | 110.97 mL | 221.95 mL |
| 0.5 mM | 4.44 mL | 22.19 mL | 44.39 mL |
| 1 mM | 2.22 mL | 11.1 mL | 22.19 mL |
| 5 mM | 0.44 mL | 2.22 mL | 4.44 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1415925-18-6 | 1415925-18-6 供应商 | 1415925-18-6 花费 | 1415925-18-6 生产商 | 订购 1415925-18-6 | 1415925-18-6 代理商