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GSK2798745

GSK2798745

Name: GSK2798745
SKU: A20799

目录号: A20799

TRPV4 ion channel blocker

GSK2798745 Chemical Structure

CAS NO. 1419609-94-1

GSK2798745 is a first-in-class, highly potent, selective, orally active transient receptor potential vanilloid 4 (TRPV4) ion channel blocker with IC50s of 1.8 and 1.6 nM for hTRPV4 and rTRPV4, respectively.

库存：现货

规格	价格	数量
1 mg	￥ 3,200.00
5 mg	￥ 9,600.00
10 mg	￥ 16,000.00

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.71 mL	108.57 mL	217.14 mL
0.5 mM	4.34 mL	21.71 mL	43.43 mL
1 mM	2.17 mL	10.86 mL	21.71 mL
5 mM	0.43 mL	2.17 mL	4.34 mL

*The above data is based on the productmolecular weight 460.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A20799
M. Wt	460.53
Formula	C25H28N6O3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1419609-94-1
Synonyms	GSK-2798745; GSK 2798745
SMILES	N#CC1=CC=C2N=CN(C[C@](CCC3)(C)C[C@@]43CN(C5=NC=C(C(C)(O)C)N=C5)C(O4)=O)C2=C1