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GSK4112是选择性的Rev-erbα激动剂,EC50值为250 nM。GSK4112是小分子化学探针, 用于核血红素受体REV-erbα的细胞生物学研究。
| In vitro | DMSO | 65 mg/mL (163.77 mM) | |
| Water | Insoluble | ||
| Ethanol | 3 mg/mL (7.55 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.2 mL | 125.98 mL | 251.95 mL |
| 0.5 mM | 5.04 mL | 25.2 mL | 50.39 mL |
| 1 mM | 2.52 mL | 12.6 mL | 25.2 mL |
| 5 mM | 0.5 mL | 2.52 mL | 5.04 mL |
*The above data is based on the productmolecular weight 396.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A17135 |
|---|---|
| 作用机制 | Agonist (激动剂) |
| M. Wt | 396.9 |
| Formula | C18H21ClN2O4S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1216744-19-2 |
| Synonyms | GSK 4112, GSK-4112 |
| SMILES | ClC(C=C1)=CC=C1CN(CC(OC(C)(C)C)=O)CC2=CC=C([N+]([O-])=O)S2 |
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