GSK591

目录号: A14374

PRMT5 inhibitor

GSK591

GSK591 Chemical Structure

CAS NO. 1616391-87-7

GSK591 is a potent selective inhibitor of the arginine methyltransferase PRMT5 with IC50 of 11 nM.

库存: 现货

规格 价格 数量
5 mg
¥ 1,000.00
10 mg
¥ 1,800.00
25 mg
¥ 3,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

GSK591 is a potent selective inhibitor of the arginine methyltransferase PRMT5 with IC50 of 11 nM.
Targets
PRMT5
4nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.28 mL 131.41 mL 262.83 mL
0.5 mM 5.26 mL 26.28 mL 52.57 mL
1 mM 2.63 mL 13.14 mL 26.28 mL
5 mM 0.53 mL 2.63 mL 5.26 mL

*The above data is based on the productmolecular weight 380.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14374
MECHANISM OF ACTION Inhibitor
M. Wt 380.48
Formula C22H28N4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1616391-87-7
Synonyms EPZ015866,GSK3203591
SMILES O=C(NC[C@H](O)CN1CCC(C=CC=C2)=C2C1)C3=CC(NC4CCC4)=NC=C3

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