GSK591

目录号: A14374

PRMT5 抑制剂

GSK591

GSK591 Chemical Structure

CAS NO. 1616391-87-7

GSK591是精氨酸甲基转移酶PRMT5的有效选择性抑制剂,IC50为11 nM。

库存: 现货

规格 价格 数量
5 mg
¥ 1,000.00
10 mg
¥ 1,800.00
25 mg
¥ 3,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

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GSK591是精氨酸甲基转移酶PRMT5的有效选择性抑制剂,IC50为11 nM。
靶点信息
PRMT5
4nM
In vitro DMSO 75 mg/mL (197.11 mM)
Water Insoluble
Ethanol 75 mg/mL (197.11 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.28 mL 131.41 mL 262.83 mL
0.5 mM 5.26 mL 26.28 mL 52.57 mL
1 mM 2.63 mL 13.14 mL 26.28 mL
5 mM 0.53 mL 2.63 mL 5.26 mL

*The above data is based on the productmolecular weight 380.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14374
作用机制 Inhibitor (抑制剂)
M. Wt 380.48
Formula C22H28N4O2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1616391-87-7
Synonyms EPZ015866,GSK3203591
SMILES O=C(NC[C@H](O)CN1CCC(C=CC=C2)=C2C1)C3=CC(NC4CCC4)=NC=C3

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