GSK690693

Name: GSK690693
SKU: A11030
Price: 245 CNY
Rating: 5 (1 reviews)

目录号: A11030

AKT 抑制剂

1 篇发表文献

GSK690693 是一种新型的 ATP 竞争性、低纳摩尔全谱 Akt 激酶抑制剂（IC50 值分别针对 Akt1、2 和 3 为 2、13 和 9 nM）。

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Grouped product items
规格	价格	库存
1mg	¥245.00	现货
5mg	¥630.00	现货
10mg	¥805.00	现货
25mg	¥1,505.00	现货
50mg	¥2,485.00	现货
100mg	¥4,165.00	现货
*10mM 1mL in DMSO**	¥490.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用GSK690693发表的1篇文献

Khan MI, .et al. , Prog Neuropsychopharmacol Biol Psychiatry, 2018, Mar 2;82:39-48 PMID: 9223784

生物活性

Discription

GSK690693 is a novel ATP-competitive, low-nanomolar pan-Akt kinase inhibitor (IC50 values are 2, 13 and 9 nM of Akt1, 2 and 3 respectively).

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11030
分子式	C21H27N7O3
分子量	425.5
CAS号	937174-76-0
SMILES	CCN1C2=C(C(=NC=C2OC[C@H]3CCCNC3)C#CC(C)(C)O)N=C1C4=NON=C4N
其他名称	GSK-690693
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	36 mg/mL (84.61 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+40%PEG300+5% tween80+50% H2O	2 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.5 mL	117.51 mL	235.02 mL
0.5 mM	4.7 mL	23.5 mL	47 mL
1 mM	2.35 mL	11.75 mL	23.5 mL
5 mM	0.47 mL	2.35 mL	4.7 mL

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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