GSK744 (S/GSK1265744)
目录号: A16014
HIV integrase 抑制剂
GSK744 是一种强效的 HIV整合酶抑制剂,可作为口服先导片剂和长效注射剂,用于治疗和预防 HIV感染。
| Discription | GSK744 is a potent HIV integrase inhibitor as an oral lead-in tablet and long-acting injectable for the treatment and prevention of HIV infection. | |||||
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| Cell Research |
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| 目录号 | A16014 |
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| 分子式 | C19H17F2N3O5 |
| 分子量 | 405.35 |
| CAS号 | 1051375-10-0 |
| SMILES | FC1=CC(F)=CC=C1CNC(C2=CN(C3=C(C2=O)O)C[C@H]4OC[C@H](C)N4C3=O)=O |
| 其他名称 | Cabotegravir |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | Warmed: 33 mg/mL (81.41 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.67 mL | 123.35 mL | 246.7 mL |
| 0.5 mM | 4.93 mL | 24.67 mL | 49.34 mL |
| 1 mM | 2.47 mL | 12.34 mL | 24.67 mL |
| 5 mM | 0.49 mL | 2.47 mL | 4.93 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2