Guanfacine hydrochloride
目录号: A15098
α2A-adrenoceptor 激动剂
盐酸古安非宁是一种抗高血压药物,它是一种选择性的α2A-肾上腺素能受体激动剂,其Kd值为31 nM,并且相对于α2B-肾上腺素能受体显示出60倍的选择性。
Discription | Guanfacine hydrochloride, an anti-hypertensive agent, is a selective α2A-adrenoceptor agonist with Kd of 31 nM and displays 60-fold selectivity over α2B-adrenoceptors. | ||
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目录号 | A15098 |
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分子式 | C9H10Cl3N3O |
分子量 | 282.55 |
CAS号 | 29110-48-3 |
SMILES | C1=CC(=C(C(=C1)Cl)CC(=O)N=C(N)N)Cl.Cl |
其他名称 | Guanfacine, Tenex, Intuniv |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 48 mg/mL (169.88 mM) | |
Water | 26 mg/mL (92.01 mM) | ||
Ethanol | 48 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 35.39 mL | 176.96 mL | 353.92 mL |
0.5 mM | 7.08 mL | 35.39 mL | 70.78 mL |
1 mM | 3.54 mL | 17.7 mL | 35.39 mL |
5 mM | 0.71 mL | 3.54 mL | 7.08 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2