GW 441756

目录号: A16238

TrkA inhibitor

GW 441756 Chemical Structure

CAS NO. 504433-23-2

GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM; little activity to c-Raf1 and CDK2.

库存: 现货

规格 价格 数量
10 mg
¥ 800.00
50 mg
¥ 2,800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM; little activity to c-Raf1 and CDK2.
Targets
TrkA CDK2 C-Raf-1
2 nM>7 μM>12 μM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 36.32 mL 181.61 mL 363.23 mL
0.5 mM 7.26 mL 36.32 mL 72.65 mL
1 mM 3.63 mL 18.16 mL 36.32 mL
5 mM 0.73 mL 3.63 mL 7.26 mL

*The above data is based on the productmolecular weight 275.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A16238
MECHANISM OF ACTION Inhibitor
M. Wt 275.31
Formula C17H13N3O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 504433-23-2
Synonyms GW-441756, GW441756
SMILES O=C1/C(C2=NC=CC=C2N1)=C\C3=CN(C)C4=C3C=CC=C4

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