GW 441756
目录号: A16238
TrkA 抑制剂
GW 441756 是一种特异性的肌球蛋白相关激酶 A (TrkA) 抑制剂，其 IC50 值为 2 nM；对 c-Raf1 和 CDK2 的活性较低。
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生物活性
| Discription | GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM; little activity to c-Raf1 and CDK2. | |||||
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| Cell Research |
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产品信息
| 目录号 | A16238 |
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| 分子式 | C17H13N3O |
| 分子量 | 275.31 |
| CAS号 | 504433-23-2 |
| SMILES | O=C1/C(C2=NC=CC=C2N1)=C\C3=CN(C)C4=C3C=CC=C4 |
| 其他名称 | GW-441756, GW441756 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 25 mg/mL (90.81 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 36.32 mL | 181.61 mL | 363.23 mL |
| 0.5 mM | 7.26 mL | 36.32 mL | 72.65 mL |
| 1 mM | 3.63 mL | 18.16 mL | 36.32 mL |
| 5 mM | 0.73 mL | 3.63 mL | 7.26 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 504433-23-2 | 504433-23-2 供应商 | 504433-23-2 花费 | 504433-23-2 生产商 | 订购 504433-23-2 | 504433-23-2 代理商