GW 5074
目录号: A11436
Raf-1 抑制剂
GW 5074 是一种强效、选择性且细胞渗透性的 c-Raf1激酶抑制剂。
| Discription | GW 5074 is a potent, selective and cell-permeable c-Raf1 kinase inhibitor | ||
|---|---|---|---|
| Targets |
|
| 目录号 | A11436 |
|---|---|
| 分子式 | C15H8Br2INO2 |
| 分子量 | 520.94 |
| CAS号 | 220904-83-6 |
| SMILES | C1=CC2=C(C=C1I)/C(=C/C3=CC(=C(C(=C3)Br)O)Br)/C(=O)N2 |
| 其他名称 | GW5074 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 101 mg/mL (193.87 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 28 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.2 mL | 95.98 mL | 191.96 mL |
| 0.5 mM | 3.84 mL | 19.2 mL | 38.39 mL |
| 1 mM | 1.92 mL | 9.6 mL | 19.2 mL |
| 5 mM | 0.38 mL | 1.92 mL | 3.84 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2