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GW 5074


Raf-1 抑制剂

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产品目录号: A11436


产品名 目录号 价格 数量
GW 5074 10mg A11436-10
¥ 800.00
GW 5074 25mg A11436-25
¥ 1,200.00
GW 5074 50mg A11436-50
¥ 1,600.00
GW 5074 100mg A11436-100
¥ 1,900.00
GW 5074 10mM * 1mL in DMSO A11436-10mM-D
¥ 600.00



GW 5074 is a potent, selective and cell-permeable c-Raf1 kinase inhibitor

GW 5074




顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A11436
Mechanism of action Inhibitor
分子量 520.94
化学分子式 C15H8Br2INO2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 220904-83-6
Synonyms GW5074
SMILES code C1=CC2=C(C=C1I)/C(=C/C3=CC(=C(C(=C3)Br)O)Br)/C(=O)N2
化学名称 3-(3,5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1,3-dihydro-indol-2-one


GW 5074 is a potent, selective and cell-permeable c-Raf1 kinase inhibitor
9 nM


Solubility (25°C) * In vitro DMSO 104 mg/mL (199.63 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.2 mL 95.98 mL 191.96mL
0.5 mM 3.84 mL 19.2 mL 38.39 mL
1 mM 1.92 mL 9.6 mL 19.2 mL
5 mM 0.38 mL 1.92 mL 3.84 mL

*The above data is based on the productmolecular weight 520.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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