GW-870086

Name: GW-870086
SKU: A18343

目录号: A18343

Glucocorticoid receptor agonist

GW-870086 Chemical Structure

CAS NO. 827319-43-7

GW-870086 is a potent anti-inflammatory agent, acting as a glucocorticoid receptor agonist, with a pIC50 of 10.1 in A549 cells expressing NF-κB.

库存：现货

规格	价格	数量
5 mg	￥ 900.00
10 mg	￥ 1,500.00
50 mg	￥ 4,500.00
100 mg	￥ 8,500.00

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产品仅用于科学研究，不针对患者销售，望谅解.

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生物活性

GW-870086 is a potent anti-inflammatory agent, acting as a glucocorticoid receptor agonist, with a pIC50 of 10.1 in A549 cells expressing NF-κB.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.87 mL	89.34 mL	178.69 mL
0.5 mM	3.57 mL	17.87 mL	35.74 mL
1 mM	1.79 mL	8.93 mL	17.87 mL
5 mM	0.36 mL	1.79 mL	3.57 mL

*The above data is based on the productmolecular weight 559.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A18343
作用机制	Agonist (激动剂)
M. Wt	559.64
Formula	C31H39F2NO6
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	827319-43-7
Synonyms	GW 870086 , GW870086
SMILES	C[C@@]12[C@](C(OCC#N)=O)(OC(C3C(C)(C)C3(C)C)=O)[C@H](C)C[C@@]1([H])[C@]4([H])C[C@H](F)C5=CC(C=C[C@]5(C)[C@@]4(F)[C@@H](O)C2)=O