GW 9662
目录号: A11984
PPARγ 拮抗剂
GW 9662 是一种选择性的 PPARγ 拮抗剂（IC50 值分别为 PPARγ 3.3 nM、PPARα 32 nM 和 PPARδ 2000 nM）。
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生物活性
| Discription | GW 9662 is a selective PPARγ antagonist (IC50 values are 3.3, 32 and 2000 nM for PPARγ, PPARα and PPARδ respectively). | ||
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产品信息
| 目录号 | A11984 |
|---|---|
| 分子式 | C13H9N2O3Cl |
| 分子量 | 276.68 |
| CAS号 | 22978-25-2 |
| SMILES | C1=CC=C(C=C1)NC(=O)C2=C(C=CC(=C2)[N+](=O)[O-])Cl |
| 其他名称 | GW9662, GW-9662 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 48 mg/mL (173.48 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 5% DMSO+corn oil | 8 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 36.14 mL | 180.71 mL | 361.43 mL |
| 0.5 mM | 7.23 mL | 36.14 mL | 72.29 mL |
| 1 mM | 3.61 mL | 18.07 mL | 36.14 mL |
| 5 mM | 0.72 mL | 3.61 mL | 7.23 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 22978-25-2 | 22978-25-2 供应商 | 22978-25-2 花费 | 22978-25-2 生产商 | 订购 22978-25-2 | 22978-25-2 代理商