GW0742
目录号: A14958
PPAR 激动剂
GW0742 是一种选择性的 PPARδ 激动剂，其 EC50 值为 1.1 nM。
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生物活性
| Discription | GW0742 is a selective agonist of PPARδ with EC50 value of 1.1 nM. | |||||
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| Targets |
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| Cell Research |
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产品信息
| 目录号 | A14958 |
|---|---|
| 分子式 | C21H17F4NO3S2 |
| 分子量 | 471.49 |
| CAS号 | 317318-84-6 |
| SMILES | CC1=C(C=CC(=C1)SCC2=C(N=C(S2)C3=CC(=C(C=C3)C(F)(F)F)F)C)OCC(=O)O |
| 其他名称 | GW-0742, GW 0742 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 86 mg/mL (182.39 mM) | |
| Water | Insoluble | ||
| Ethanol | 40 mg/mL (84.84 mM) | ||
| In vivo | 2% DMSO+40% PEG 300+2% Tween 80+ddH2O | 2 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.21 mL | 106.05 mL | 212.09 mL |
| 0.5 mM | 4.24 mL | 21.21 mL | 42.42 mL |
| 1 mM | 2.12 mL | 10.6 mL | 21.21 mL |
| 5 mM | 0.42 mL | 2.12 mL | 4.24 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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