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CSF-1R 抑制剂

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产品目录号: A11959


产品名 目录号 价格 数量
GW2580 25mg A11959-25
¥ 400.00
GW2580 50mg A11959-50
¥ 700.00
GW2580 100mg A11959-100
¥ 900.00
GW2580 200mg A11959-200
¥ 1,400.00
GW2580 10mM * 1mL in DMSO A11959-10mM-D
¥ 700.00



GW2580 is a small-molecule, ATP-competitive inhibitor of cFMS kinase.





顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 GW2580 发表的文献 (1)
  • Liu M, .et al. Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47?mediated &don*t-eat-me* signal, Nat Immunol, 2019, Jan 21 PMID: 30664738

Chemical Information

目录号 A11959
Mechanism of action Inhibitor
分子量 366.41
化学分子式 C??H??N?O?
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 870483-87-7
Synonyms GW 2580, GW-2580
化学名称 5-(3-Methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine


GW2580 is a small-molecule, ATP-competitive inhibitor of cFMS kinase.


Solubility (25°C) * In vitro DMSO 48 mg/mL (131 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% hydroxyethyl cellulose/0.1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.29 mL 136.46 mL 272.92mL
0.5 mM 5.46 mL 27.29 mL 54.58 mL
1 mM 2.73 mL 13.65 mL 27.29 mL
5 mM 0.55 mL 2.73 mL 5.46 mL

*The above data is based on the productmolecular weight 366.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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