GW4064

目录号: A11141

FXR agonist

GW4064 Chemical Structure

CAS NO. 278779-30-9

GW4064 is a selective, non-steroidal farnesoid X receptor (FXR) agonist (EC50 = 15 nM).

库存: 现货

规格 价格 数量
10 mg
¥ 800.00
50 mg
¥ 2,500.00
100 mg
¥ 4,500.00
200 mg
¥ 8,500.00
10mM * 1mL in DMSO
¥ 600.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

GW4064 is a selective, non-steroidal farnesoid X receptor (FXR) agonist (EC50 = 15 nM).
Targets
FXR (CV1)
65 nM(EC50)
In vitro (25°C) DMSO 109 mg/mL (200.79 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% methylcellulose 11 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.42 mL 92.11 mL 184.23 mL
0.5 mM 3.68 mL 18.42 mL 36.85 mL
1 mM 1.84 mL 9.21 mL 18.42 mL
5 mM 0.37 mL 1.84 mL 3.68 mL

*The above data is based on the productmolecular weight 542.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11141
MECHANISM OF ACTION Agonist
M. Wt 542.8
Formula C28H22Cl3NO4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 278779-30-9
Synonyms GW-4064
SMILES CC(C)C1=C(C(=NO1)C2=C(C=CC=C2Cl)Cl)COC3=CC(=C(C=C3)/C=C/C4=CC(=CC=C4)C(=O)O)Cl

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