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FXR 激动剂

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产品目录号: A11141


产品名 目录号 价格 数量
GW4064 10mg A11141-10
¥ 800.00
GW4064 50mg A11141-50
¥ 2,500.00
GW4064 100mg A11141-100
¥ 4,500.00
GW4064 200mg A11141-200
¥ 8,500.00
GW4064 10mM * 1mL in DMSO A11141-10mM-D
¥ 600.00



GW4064 is a selective, non-steroidal farnesoid X receptor (FXR) agonist (EC50 = 15 nM).





顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 GW4064 发表的文献 (1)
  • Takae K, .et al. Evidence for the involvement of FXR signaling in ovarian granulosa cell function, J Reprod Dev, 2018, Nov 16 PMID: 30449821

Chemical Information

目录号 A11141
Mechanism of action Agonist
分子量 542.8
化学分子式 C28H22Cl3NO4
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 278779-30-9
Synonyms GW-4064
SMILES code CC(C)C1=C(C(=NO1)C2=C(C=CC=C2Cl)Cl)COC3=CC(=C(C=C3)/C=C/C4=CC(=CC=C4)C(=O)O)Cl
化学名称 3-[2-[2-Chloro-4-[[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methoxy]phenyl]ethenyl]benzoic acid


GW4064 is a selective, non-steroidal farnesoid X receptor (FXR) agonist (EC50 = 15 nM).
65 nM(EC50)


Solubility (25°C) * In vitro DMSO 109 mg/mL (200.79 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% methylcellulose 11 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.42 mL 92.11 mL 184.23mL
0.5 mM 3.68 mL 18.42 mL 36.85 mL
1 mM 1.84 mL 9.21 mL 18.42 mL
5 mM 0.37 mL 1.84 mL 3.68 mL

*The above data is based on the productmolecular weight 542.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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