GW4064

Name: GW4064
SKU: A11141

目录号: A11141

FXR 激动剂

Product Citations (2)

GW4064 Chemical Structure

CAS NO. 278779-30-9

GW4064是选择性的非甾体类法尼醇X受体（FXR）激动剂（EC50 = 15 nM）。

库存：现货

规格	价格	数量
10 mg	￥ 800.00
50 mg	￥ 2,500.00
100 mg	￥ 4,500.00
200 mg	￥ 8,500.00
10mM * 1mL in DMSO	￥ 600.00

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生物活性

GW4064是选择性的非甾体类法尼醇X受体（FXR）激动剂（EC50 = 15 nM）。

靶点信息

FXR (CV1)
65 nM(EC50)

溶解度 *

In vitro (25°C)	DMSO	99 mg/mL (182.37 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% methylcellulose	10 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.42 mL	92.11 mL	184.23 mL
0.5 mM	3.68 mL	18.42 mL	36.85 mL
1 mM	1.84 mL	9.21 mL	18.42 mL
5 mM	0.37 mL	1.84 mL	3.68 mL

*The above data is based on the productmolecular weight 542.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11141
作用机制	Agonist (激动剂)
M. Wt	542.8
Formula	C28H22Cl3NO4
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	278779-30-9
Synonyms	GW-4064
SMILES	CC(C)C1=C(C(=NO1)C2=C(C=CC=C2Cl)Cl)COC3=CC(=C(C=C3)/C=C/C4=CC(=CC=C4)C(=O)O)Cl