GW788388
目录号: A11083
TGF-beta/Smad 抑制剂
GW788388 是一种强效的、口服活性的、选择性的转化生长因子β受体I（TGF-βR1）（激活素样激酶5，ALK5）抑制剂。
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生物活性
| Discription | GW788388 is a potent, orally active and selective inhibitor of transforming growth factor beta receptor I (TGF-βR1) (activin receptor-like kinase 5, ALK5). | |||||
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| Cell Research |
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产品信息
| 目录号 | A11083 |
|---|---|
| 分子式 | C25H23N5O2 |
| 分子量 | 425.5 |
| CAS号 | 452342-67-5 |
| SMILES | C1COCCC1NC(=O)C2=CC=C(C=C2)C3=NC=CC(=C3)C4=C(NN=C4)C5=CC=CC=N5 |
| 其他名称 | GW-788388 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 15 mg/mL (35.25 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.5 mL | 117.51 mL | 235.02 mL |
| 0.5 mM | 4.7 mL | 23.5 mL | 47 mL |
| 1 mM | 2.35 mL | 11.75 mL | 23.5 mL |
| 5 mM | 0.47 mL | 2.35 mL | 4.7 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 452342-67-5 | 452342-67-5 供应商 | 452342-67-5 花费 | 452342-67-5 生产商 | 订购 452342-67-5 | 452342-67-5 代理商