GW788388

目录号: A11083

TGF-beta/Smad inhibitor

GW788388

GW788388 Chemical Structure

CAS NO. 452342-67-5

GW788388 is a potent, orally active and selective inhibitor of transforming growth factor beta receptor I (TGF-βR1) (activin receptor-like kinase 5, ALK5).

库存: 现货

规格 价格 数量
5 mg
¥ 380.00
10 mg
¥ 600.00
50 mg
¥ 2,000.00
100 mg
¥ 3,600.00
10mM * 1mL in DMSO
¥ 910.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

GW788388 is a potent, orally active and selective inhibitor of transforming growth factor beta receptor I (TGF-βR1) (activin receptor-like kinase 5, ALK5).
Targets
ALK5 (Cell-free assay)
18 nM
In vitro (25°C) DMSO 15 mg/mL (35.25 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.5 mL 117.51 mL 235.02 mL
0.5 mM 4.7 mL 23.5 mL 47 mL
1 mM 2.35 mL 11.75 mL 23.5 mL
5 mM 0.47 mL 2.35 mL 4.7 mL

*The above data is based on the productmolecular weight 425.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A11083
MECHANISM OF ACTION Inhibitor
M. Wt 425.5
Formula C25H23N5O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 452342-67-5
Synonyms GW-788388
SMILES C1COCCC1NC(=O)C2=CC=C(C=C2)C3=NC=CC(=C3)C4=C(NN=C4)C5=CC=CC=N5

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