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GW806742X is a Mixed Lineage Kinase Domain-Like protein (MLKL) inhibitor which binds the MLKL pseudokinase domain with a Kd value of 9.3 μM and has anti-necroptosis activity. GW806742X has activity against VEGFR2.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.44 mL | 87.18 mL | 174.35 mL |
| 0.5 mM | 3.49 mL | 17.44 mL | 34.87 mL |
| 1 mM | 1.74 mL | 8.72 mL | 17.44 mL |
| 5 mM | 0.35 mL | 1.74 mL | 3.49 mL |
*The above data is based on the productmolecular weight 573.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A19569 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 573.55 |
| Formula | C25H22F3N7O4S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 579515-63-2 |
| Synonyms | GW 806742X, GW-806742X |
| SMILES | O=S(C1=CC=CC(NC2=NC=CC(N(C)C3=CC=C(NC(NC4=CC=C(OC(F)(F)F)C=C4)=O)C=C3)=N2)=C1)(N)=O |
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