GW842166X
目录号: A11253
CB2 receptor 激动剂
GW842166X 是一种选择性的非大麻素 CB2 受体激动剂,目前正在作为一种新型口服治疗炎症性疼痛的药物进行临床开发。
Discription | GW842166X is a selective non-cannabinoid CB2 receptor agonist, which is undergoing clinical development as a novel oral treatment for inflammatory pain | |||||
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Cell Research |
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目录号 | A11253 |
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分子式 | C18H17Cl2F3N4O2 |
分子量 | 449.25 |
CAS号 | 666260-75-9 |
SMILES | C1COCCC1CNC(=O)C2=CN=C(N=C2C(F)(F)F)NC3=C(C=C(C=C3)Cl)Cl |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 18 mg/mL (40.06 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 22.26 mL | 111.3 mL | 222.59 mL |
0.5 mM | 4.45 mL | 22.26 mL | 44.52 mL |
1 mM | 2.23 mL | 11.13 mL | 22.26 mL |
5 mM | 0.45 mL | 2.23 mL | 4.45 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2