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CB2 receptor 激动剂

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产品目录号: A11253


产品名 目录号 价格 数量
GW842166X 5mg A11253-5
¥ 600.00
GW842166X 10mg A11253-10
¥ 1,000.00
GW842166X 25mg A11253-25
¥ 2,000.00
GW842166X 10mM * 1mL in DMSO A11253-10mM-D
¥ 1,130.00



GW842166X is a selective non-cannabinoid CB2 receptor agonist, which is undergoing clinical development as a novel oral treatment for inflammatory pain





顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A11253
Mechanism of action Agonist
分子量 449.25
化学分子式 C18H17Cl2F3N4O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 666260-75-9, 956013-38-0
Synonyms N/A
化学名称 2-(2,4-dichlorophenylamino)-N-((tetrahydro-2H-pyran-4-yl)methyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide


GW842166X is a selective non-cannabinoid CB2 receptor agonist, which is undergoing clinical development as a novel oral treatment for inflammatory pain
63 nM(EC50)


Solubility (25°C) * In vitro DMSO 20 mg/mL (44.51 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.26 mL 111.3 mL 222.59mL
0.5 mM 4.45 mL 22.26 mL 44.52 mL
1 mM 2.23 mL 11.13 mL 22.26 mL
5 mM 0.45 mL 2.23 mL 4.45 mL

*The above data is based on the productmolecular weight 449.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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