Trusted by 10,000+ Scientists since 2006

GZD824 Dimesylate

Bcr-Abl 抑制剂

0 Customer Reviews
产品目录号: A15849


产品名 目录号 价格 数量
GZD824 5mg A15849-5
¥ 900.00
GZD824 10mg A15849-10
¥ 1,500.00
GZD824 25mg A15849-25
¥ 2,800.00



GZD824 is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I) with IC50 of 0.34 nM and 0.68 nM, respectively.

GZD824 Dimesylate




顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A15849
Mechanism of action Inhibitor
分子量 724.77
化学分子式 C29H27F3N6O.2CH4O3S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1421783-64-3
Synonyms GZD-824 Dimesylate
SMILES code CC1=CC=C(C(NC2=CC=C(CN3CCN(C)CC3)C(C(F)(F)F)=C2)=O)C=C1C#CC4=CN=C5C(C=NN5)=C4.CS(=O)(O)=O.CS(=O)(O)=O
化学名称 3-((1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide dimethanesulfonate


GZD824 is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I) with IC50 of 0.34 nM and 0.68 nM, respectively.
Target Value
Abl(Q252H)IC50: 0.15nM
Abl(E255K)IC50: 0.27nM
Abl(M351T)IC50: 0.29nM
AblIC50: 0.34nM
Abl(H396P)IC50: 0.35nM
Abl(Y253F)IC50: 0.35nM
Abl(T315I)IC50: 0.68nM
Abl(G250E)IC50: 0.71nM


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 13.8 mL 68.99 mL 137.97mL
0.5 mM 2.76 mL 13.8 mL 27.59 mL
1 mM 1.38 mL 6.9 mL 13.8 mL
5 mM 0.28 mL 1.38 mL 2.76 mL

*The above data is based on the productmolecular weight 724.77. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Ordering online

To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.

To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.

When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards.  We will then liaise with you or your purchasing department to confirm the order.

Found your products but not ready to order?

Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.

Ordering offline

You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order.  Our contact details are:

We require the following information to process your order:
  • The catalog number for each product. 
  • Your email address or fax number. 
  • Your name and telephone number. 
  • Shipping address and billing address.
  • Purchase order numbers.



Keywords:购买 GZD824 Dimesylate | GZD824 Dimesylate 供应商 | 订购 GZD824 Dimesylate | GZD824 Dimesylate 价格 | GZD824 Dimesylate 生产商 | 订单 GZD824 Dimesylate | GZD824 Dimesylate 代理商 | 购买 1421783-64-3| 1421783-64-3 供应商 | 订购 1421783-64-3 | 1421783-64-3 价格 | 1421783-64-3 生产商 | 订单 1421783-64-3 | 1421783-64-3 代理商|buy GZD824 Dimesylate | GZD824 Dimesylate Supplier | purchase GZD824 Dimesylate | GZD824 Dimesylate cost | GZD824 Dimesylate manufacturer | order GZD824 Dimesylate | GZD824 Dimesylate distributor | buy 1421783-64-3| 1421783-64-3 Supplier | purchase 1421783-64-3 | 1421783-64-3 cost | 1421783-64-3 manufacturer | order 1421783-64-3 | 1421783-64-3 distributor