H3B-6527
目录号: A16252
FGFR4 抑制剂
H3B-6527 是一种高度选择性的 FGFR4 抑制剂,在 FGF19 扩增的细胞系和小鼠中具有强大的抗肿瘤活性。
Discription | H3B-6527 is a highly selective FGFR4 inhibitor with potent antitumour activity in FGF19 amplified cell lines and mice. |
---|
目录号 | A16252 |
---|---|
分子式 | C29H34Cl2N8O4 |
分子量 | 629.54 |
CAS号 | 1702259-66-2 |
SMILES | C=CC(NC1=CC(N2CCN(CC)CC2)=CC=C1NC3=NC=NC(N(C(NC4=C(Cl)C(OC)=CC(OC)=C4Cl)=O)C)=C3)=O |
其他名称 | H3B6527, H3B 6527 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 45 mg/mL (71.48 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 15.88 mL | 79.42 mL | 158.85 mL |
0.5 mM | 3.18 mL | 15.88 mL | 31.77 mL |
1 mM | 1.59 mL | 7.94 mL | 15.88 mL |
5 mM | 0.32 mL | 1.59 mL | 3.18 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2