HC-030031
            目录号: A13278
    
            TRPA1 抑制剂
    
								
							HC-030031 是一种选择性的 TRPA1 阻断剂,能够抑制由 AITC 和甲醛 (IC50 分别为 6.2 和 5.3 微摩尔) 引起的 TRPA1 介导的钙流入。
        | Discription | HC-030031 is a selective TRPA1 blocker, antagonizing TRPA1-mediated calcium influx induced by AITC and formalin (IC50 = 6.2 and 5.3 uM, respectively). | |||||
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| 目录号 | A13278 | 
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| 分子式 | C18H21N5O3 | 
| 分子量 | 355.4 | 
| CAS号 | 349085-38-7 | 
| SMILES | CC(C)C1=CC=C(C=C1)NC(=O)CN2C=NC3=C2C(=O)N(C(=O)N3C)C | 
| 其他名称 | HC030031 | 
| 储存条件 | Store lyophilized at -20ºC, keep desiccated.   | 
				
| In vitro (25°C) | DMSO | 27 mg/mL (75.97 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 0.5% methylcellulose | 28 mg/mL | |
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										  *  <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.  | 
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg | 
|---|---|---|---|
| 0.1 mM | 28.14 mL | 140.69 mL | 281.37 mL | 
| 0.5 mM | 5.63 mL | 28.14 mL | 56.27 mL | 
| 1 mM | 2.81 mL | 14.07 mL | 28.14 mL | 
| 5 mM | 0.56 mL | 2.81 mL | 5.63 mL | 
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2