Hesperadin

目录号: A10448

Aurora B Kinase 抑制剂

Hesperadin

Hesperadin Chemical Structure

CAS NO. 422513-13-1

Hesperadin是一种人极光B抑制剂,IC50为40 nM,用于防止底物磷酸化。它显著降低AMPK、Lck、MKK1、MAPKAP-K1、CHK1和PHK的活性,而不抑制MKK1在体内的活性。

库存: 现货

规格 价格 数量
5 mg
¥ 540.00
10 mg
¥ 920.00
50 mg
¥ 2,700.00
100 mg
¥ 9,180.00
10mM * 1mL in DMSO
¥ 1,520.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Hesperadin是一种人极光B抑制剂,IC50为40 nM,用于防止底物磷酸化。它显著降低AMPK、Lck、MKK1、MAPKAP-K1、CHK1和PHK的活性,而不抑制MKK1在体内的活性。
靶点信息
TbAUK1 (Cell-free assay) Aurora B (human) (Cell-free assay)
40 nM250 nM
In vitro (25°C) DMSO 100 mg/mL (193.55 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+40%PEG300+5% tween80+50% H2O 2.3 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.35 mL 96.77 mL 193.54 mL
0.5 mM 3.87 mL 19.35 mL 38.71 mL
1 mM 1.94 mL 9.68 mL 19.35 mL
5 mM 0.39 mL 1.94 mL 3.87 mL

*The above data is based on the productmolecular weight 516.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10448
作用机制 Inhibitor (抑制剂)
M. Wt 516.7
Formula C29H32N4O3S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 422513-13-1
SMILES CCS(=O)(=O)NC1=CC\2=C(C=C1)NC(=O)/C2=C(/C3=CC=CC=C3)\NC4=CC=C(C=C4)CN5CCCCC5

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