Hesperetin

目录号: A10449

PDE4 inhibitor

Hesperetin Chemical Structure

CAS NO. 520-33-2

Hesperetin, a selective phosphodiesterase (PDE)4 inhibitor, is present in the traditional Chinese medicine, “Chen Pi.” Hesperetin is a citrus flavonoid that has been reported to lower plasma cholesterol. Hesperetin reduces the transcription of ACAT-2 mRNA in Hep-G2 cells and reduces ApoB protein synthesis in a dose-dependent manner. It also is a potential therapy for carcinoid cancer.

库存: 现货

规格 价格 数量
5 mg
¥ 400.00
10 mg
¥ 500.00
50 mg
¥ 600.00
100 mg
¥ 800.00
10mM * 1mL in DMSO
¥ 500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Hesperetin, a selective phosphodiesterase (PDE)4 inhibitor, is present in the traditional Chinese medicine, “Chen Pi.” Hesperetin is a citrus flavonoid that has been reported to lower plasma cholesterol. Hesperetin reduces the transcription of ACAT-2 mRNA in Hep-G2 cells and reduces ApoB protein synthesis in a dose-dependent manner. It also is a potential therapy for carcinoid cancer.
Targets
Histamine receptor TGF-β
In vitro DMSO 60 mg/mL (198.49 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.08 mL 165.4 mL 330.8 mL
0.5 mM 6.62 mL 33.08 mL 66.16 mL
1 mM 3.31 mL 16.54 mL 33.08 mL
5 mM 0.66 mL 3.31 mL 6.62 mL

*The above data is based on the productmolecular weight 302.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10449
MECHANISM OF ACTION Inhibitor
M. Wt 302.3
Formula C16H14O6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 520-33-2
Synonyms N/A
SMILES COC1=C(C=C(C=C1)[C@@H]2CC(=O)C3=C(C=C(C=C3O2)O)O)O

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